Transcatheter Aortic Valve Replacement / Transcatheter Aortic Valve Implantation (TAVR / TAVI)

What is Aortic stenosis

Aortic stenosis involves narrowing of the aortic valve which obstructs the blood flow from the heart to the body.

Symptoms of Aortic stenosis

Chest pain on exertion.

Breathlessness on exertion.

Dizziness/Blackout on exertion.

Diagnosis of Aortic stenosis

Clinical Examination.

ECG.

Two dimensional echocardiogram.

Progress of the disease

When it becomes severe it causes symptoms and reduces the life span of the patient.

Prognosis of the disease

Poor if untreated, 5 years survival rate of less than 10 %.

If patient has symptoms of heart failure , then median survival is 2 years.

Treatment options for Aortic stenosis

TAVR / TAVI (Transcatheter aortic valve replacement / Transcatheter aortic valve implantation)

SAVR (Surgical aortic valve replacement)

Types of TAVR valves

Balloon expandable (Sapien 3, Myval)

Self expandable (Evolut R, Accurate Neo, Portico, Lotus edge)




Advantages of TAVR over surgical aortic valve replacement (SAVR)

Who benefits most from TAVR

Patients with symptomatic severe degenerative tricuspid aortic valve stenosis need to be evaluated by a multidisciplinary team of specialist doctors. It involves assessment of other co morbidities such as chronic kidney disease, chronic lung disease, malignancies, autoimmune diseases, previous cardiac surgeries etc which increase the procedural risk. It also involves frailty assessment. CT scan of heart and peripheral vessels and coronary angiogram are a pre-requisite. All patients with symptomatic severe degenerative tricuspid aortic valve stenosis and patients with symptomatic dysfunctional biological aortic valves (surgical / transcatheter) benefit most from TAVR.